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Metabolic Nutrition E.S.P Extreme High – Stimulant Pre-Workout 50/25

Metabolic Nutrition 50/25

from £32.24

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Metabolic Nutrition E.S.P. Extreme is a hardcore pre-workout created for advanced users who demand maximum energy, intensity, and focus from their training. What makes this formula stand out is its fully adjustable dosing system, which allows users to choose between 1, 2, or 3 scoops, depending on their stimulant tolerance and training demands. This isn't a pre-workout for beginners — it's designed for those who want a no-compromise kick before hitting the gym.

With three distinct blends targeting energy, focus, and endurance, E.S.P. Extreme delivers a robust and sustained training experience from start to finish.

Who is it for?

E.S.P. Extreme is best suited for:

  • Experienced pre-workout users with high stimulant tolerance

  • Individuals training in high-intensity or strength-focused disciplines

  • Athletes who prefer customisable dosing depending on their session

  • Users seeking sharp focus, long-lasting energy, and a strong mental push

Not recommended for beginners, stimulant-sensitive individuals, or those training late in the day.

Our opinion

E.S.P. Extreme does precisely what it promises — the energy hits fast and hard, and the mental focus is one of the best we've felt in this category. The three-scoop system makes it super flexible, and even one scoop packs more of a punch than many full servings of other pre-workouts. There's no pump blend here; it's all about pure drive, alertness, and energy. If you're stim-tolerant and want a product that delivers consistently, this is a safe bet.

Ingredient Breakdown (per 3 scoops / 16.5g)


Extreme Energy Matrix – 600mg total caffeine


This formula combines:


  • Caffeine Anhydrous
    Delivers fast-acting energy, mental alertness, and drive.


  • Di-Caffeine Malate
    A slower-releasing form of caffeine that helps prevent the crash.


  • Theobromine
    A milder stimulant related to caffeine, supporting mood and longer-lasting stimulation.


Together, these three ingredients form a high-energy matrix that delivers an intense yet balanced wave of energy, characterised by a rapid onset and extended duration.

Extreme Mental Matrix – 1,000mg




  • Choline Bitartrate
    Included for its role in acetylcholine production, which is associated with sharper focus and faster reaction times during training.


  • N-Acetyl L-Tyrosine
    A stable form of L-Tyrosine that supports dopamine and norepinephrine production — neurotransmitters involved in mental alertness, motivation, and stress response.


  • Eria Jarensis
    A well-known focus enhancer and mood booster, Eria Jarensis is a popular choice in high-stim pre-workouts for its euphoric-like effects and heightened mental drive.


Extreme Endurance Matrix – 5,001mg




  • Beta-Alanine
    Included at an aggressive dose, beta-alanine supports endurance and training volume by buffering lactic acid. The tingling (paresthesia) sensation is intense with three scoops and is often used as an indicator of intensity by experienced users.


Extreme Absorption Matrix




  • Black Pepper Extract
    Enhances the bioavailability of the entire formula, ensuring faster uptake and greater ingredient effectiveness.


Electrolyte & B-Vitamin Matrix


The product also includes a blend of key vitamins (B6, B12, B3), minerals (sodium, potassium, calcium, magnesium), and electrolytes. These support hydration and muscle function, especially during intense training sessions where sweat loss can impact performance.

Dosage – Timing – Follow-Up


Start with one scoop (5.5g) mixed with water 20–30 minutes before training to assess tolerance.
Depending on your caffeine tolerance and training intensity, increase to 2 or 3 scoops.
Do not exceed three scoops (16.5g) in 24 hours.
Stay hydrated and avoid combining with other sources of caffeine.

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Need help?

Metabolic Nutrition E.S.P. Extreme High-Stimulant Pre-Workout is a hardcore pre-workout powder built around an adjustable 1-to-3-scoop dosing system, giving between 5.5g and 16.5g per serving. The product page describes it as created for advanced users who demand maximum energy, intensity and focus.

Metabolic Nutrition E.S.P. Extreme combines an Extreme Energy Matrix of caffeine anhydrous, di-caffeine malate and theobromine (600mg total caffeine at three scoops), an Extreme Mental Matrix of choline bitartrate, N-acetyl L-tyrosine and Eria Jarensis (1,000mg), an Extreme Endurance Matrix of beta-alanine (5,001mg), and black pepper extract for absorption.

Yes, Metabolic Nutrition E.S.P. Extreme is stimulant based, with its Extreme Energy Matrix providing 600mg of total caffeine from caffeine anhydrous, di-caffeine malate and theobromine at a full three-scoop serving, plus Eria Jarensis. With this much stimulant content, it is not recommended to take a dose late in the day.

Eria Jarensis is included in the Extreme Mental Matrix of Metabolic Nutrition E.S.P. Extreme, dosed as part of a 1,000mg blend alongside choline bitartrate and N-acetyl L-tyrosine. The product page describes it as a well-known focus enhancer and mood booster popular in high-stimulant pre-workouts.

Metabolic Nutrition E.S.P. Extreme is built around a 600mg caffeine energy matrix, a 1,000mg mental matrix including Eria Jarensis and N-acetyl L-tyrosine for focus, a 5,001mg beta-alanine endurance matrix for training volume, and black pepper extract to support absorption of the full formula.

According to the label, Metabolic Nutrition E.S.P. Extreme should be started at one scoop (5.5g) mixed with water 20-30 minutes before training to assess tolerance, then increased to 2 or 3 scoops depending on caffeine tolerance and training intensity.

No. The product page states directly that Metabolic Nutrition E.S.P. Extreme is not a pre-workout for beginners, describing it as a hardcore formula created for advanced users who want a no-compromise kick before training.

Metabolic Nutrition E.S.P. Extreme can commonly be stacked with non-stimulant products such as creatine, intra-workout aminos, or a post-workout protein shake. Because it is a high-stimulant pre-workout, it should not be combined with other stimulant products, including fat burners or additional pre-workout formulas.

Metabolic Nutrition E.S.P. Extreme High-Stimulant Pre-Workout is intended for healthy adults over the age of 18. Do not exceed the recommended serving. Because this is a high-stimulant formula, avoid taking it late in the day and do not combine it with other stimulant products. If you are pregnant, breastfeeding, taking medication or have a pre-existing medical condition, consult a doctor before use.

Metabolic Nutrition E.S.P. Extreme High-Stimulant Pre-Workout is available through Cross The Limits, an authorised UK retailer. Orders placed before 4pm are dispatched the same day, with free UK shipping on orders over £89.

Metabolic Nutrition

Metabolic Nutrition

Metabolic Nutrition – Scientifically Engineered Supplements for Peak Performance

At Cross the Limits, we are proud of our approach to stocking only the finest quality products for our customers, and Metabolic Nutrition supplements are no different. They’re a trusted brand with over 30 years of expertise in developing fitness supplements that truly work. Founded by a clinical pharmacist and nutritionist, Dr. Cohen, Metabolic Nutrition has revolutionised the supplement industry by focusing not just on the “coolness” factor, but mixing in precision, quality, and—most of all—scientifically validated formulations.