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Metabolic Nutrition Insulean

Metabolic Nutrition 90 Capsules

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Metabolic Nutrition Insulean 90 Capsules is an advanced carbohydrate partitioning and metabolic support formula designed to support glucose metabolism, insulin function, nutrient utilisation and body composition.

Featuring 500 mg Berberine 97%, 500 mg Gymnema Sylvestre, 300 mg Alpha Lipoic Acid and 200 mcg Chromium, Insulean combines glucose metabolism ingredients with thermogenic compounds to create a comprehensive formula for carbohydrate management.

Developed by American supplement manufacturer Metabolic Nutrition, Insulean is designed for athletes, bodybuilders and individuals looking to optimise carbohydrate utilisation during bulking, cutting or body recomposition phases.

What Is Metabolic Nutrition Insulean?


Metabolic Nutrition Insulean is an insulin mimetic and glucose disposal supplement, often referred to as a GDA (Glucose Disposal Agent).

Its formula combines ingredients associated with insulin signalling, carbohydrate metabolism, glucose utilisation and thermogenic activity.

Key Benefits



  • Carbohydrate Metabolism: Berberine, Chromium and Alpha Lipoic Acid support pathways involved in glucose utilisation.

  • Insulin Function: Chromium contributes to maintaining normal blood glucose levels.

  • Glucose Partitioning: Formulated around mechanisms involved in carbohydrate uptake and energy storage.

  • Muscle Glycogen Support: Designed to complement carbohydrate intake during demanding training periods.

  • Appetite & Craving Management: Gymnema Sylvestre is traditionally used in formulas targeting sugar cravings and appetite.

  • Thermogenic Support: Grains of Paradise, Citrus Aurantium and Capsicum Extract complement the metabolic formula.

  • Energy Metabolism: B vitamins contribute to normal energy-yielding metabolism.


Insulean is particularly relevant to individuals following structured, carbohydrate-containing diets who want a more specialised approach to metabolic supplementation.

Metabolic Nutrition Insulean Supplement Facts


Container Size: 90 Capsules
Serving Size: 3 Capsules
Servings Per Container: 30
Active Ingredients Per Serving:

  • Vitamin B12 (as Cyanocobalamin) – 102.6 mcg

  • Vitamin B3 (as Niacinamide) – 20 mg

  • Vitamin B6 (as Pyridoxine HCl) – 4.3 mg

  • Chromium (as Chromium Polynicotinate) – 200 mcg

  • Gymnema Sylvestre Powder – 500 mg

  • Berberine 97% – 500 mg

  • Alpha Lipoic Acid – 300 mg

  • Grains of Paradise – 100 mg

  • Citrus Aurantium – 100 mg

  • Theacrine – 50 mg

  • Evodiamine – 50 mg

  • Vanadyl Sulfate – 30 mg

  • Capsicum Extract – 5 mg

  • Black Pepper Extract – 5 mg


Other Ingredients: Magnesium Silicate, Magnesium Stearate, Calcium Carbonate, Titanium Dioxide, Gelatin Capsule, Silicon Dioxide, Stearic Acid, FD&C Yellow #5 and FD&C Yellow #6.

Ingredient Breakdown



  • Gymnema Sylvestre – 500 mg: A botanical ingredient traditionally used in blood sugar and appetite-support formulations. Its naturally occurring gymnemic acids are associated with glucose metabolism and sweet-taste perception.

  • Berberine 97% – 500 mg: A concentrated plant alkaloid investigated for its effects on AMPK signalling, insulin sensitivity and glucose and lipid metabolism. One of the principal ingredients in the formula’s carbohydrate-management system.

  • Alpha Lipoic Acid – 300 mg: An antioxidant compound involved in mitochondrial energy metabolism. Frequently included in glucose disposal formulas because of its relationship with insulin signalling and cellular glucose uptake.

  • Chromium – 200 mcg: An essential trace mineral that contributes to the maintenance of normal blood glucose levels and normal macronutrient metabolism.

  • Grains of Paradise – 100 mg: A botanical ingredient containing compounds such as 6-Paradol, investigated for thermogenesis, brown adipose tissue activity and energy expenditure.

  • Citrus Aurantium – 100 mg: Bitter Orange Extract, commonly included in thermogenic and weight-management formulations for its naturally occurring adrenergically active compounds.

  • Theacrine – 50 mg: An alkaloid structurally related to caffeine, used in energy and performance supplements for its stimulant-related properties and effects on alertness.

  • Evodiamine – 50 mg: A plant-derived alkaloid investigated for its interactions with thermogenic and metabolic signalling pathways.

  • Vanadyl Sulfate – 30 mg: A vanadium compound researched for insulin-mimetic activity and its interactions with cellular glucose-related pathways.

  • Capsicum Extract – 5 mg: Contains compounds associated with heat production, thermogenesis and energy metabolism.

  • Black Pepper Extract – 5 mg: Provides piperine-related compounds associated with ingredient absorption and metabolic enzyme activity.

  • Vitamin B3 – 20 mg: Contributes to normal energy-yielding metabolism and the reduction of tiredness and fatigue.

  • Vitamin B6 – 4.3 mg: Supports normal protein and glycogen metabolism, energy production and normal nervous system function.

  • Vitamin B12 – 102.6 mcg: Contributes to normal energy metabolism, red blood cell formation and the reduction of tiredness and fatigue.


How to Take Metabolic Nutrition Insulean


According to Metabolic Nutrition’s recommended directions:

  • Meals containing 30–60 g carbohydrates: Take 1–2 capsules with the meal.

  • Meals containing 75–150 g carbohydrates or more: Take 2–3 capsules with the meal.

  • Maximum per carbohydrate-containing meal: 3 capsules.


Follow the manufacturer’s directions and do not exceed the recommended dosage.
Insulean contains ingredients that influence glucose metabolism and stimulant-related pathways. It is not suitable for people with diabetes or certain cardiovascular conditions, or those taking medication, without appropriate medical guidance.
METABOLIC NUTRITION INSULEAN – CARBOHYDRATE CONTROL. METABOLIC SUPPORT. ADVANCED NUTRIENT PARTITIONING.

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Insulean is a supplement designed to support healthy blood sugar and insulin response, combining B vitamins with compounds like chromium, Gurmar, and berberine alongside thermogenic ingredients.

B vitamins are involved in many metabolic processes, and a deficiency can negatively affect these processes, so Insulean provides an additional dietary portion of them.

Chromium helps the body maintain proper blood sugar levels and affects insulin production, making it important for carbohydrate metabolism.

Gurmar leaves contain compounds that support insulin production and modify taste bud receptors, reducing the appetite for sweets.

Berberine is a natural alkaloid that effectively lowers blood sugar levels, with some researchers noting its mechanism resembles that of diabetes medications.

ALA occurs naturally in the body in small amounts; supplementing it increases cells’ sensitivity to sugars and aids in glycogen production.

Grains of Paradise seeds, extracted from the Madagascar frame, promote the synthesis of hormones such as norepinephrine and have a thermogenic effect that accelerates fat burning.

Theacrine is described as an alternative to caffeine, providing a stimulating effect while supporting liver function and potentially lowering LDL (bad) cholesterol.

Vanadyl sulfate mimics the action of insulin once in the body, increasing the body’s sensitivity to insulin, with some studies suggesting a positive effect on building muscle mass.

Capsules should be taken with a meal containing carbohydrates; the manufacturer recommends taking 2-3 capsules at a time, adjusted according to needs and the amount of carbohydrates consumed.

Metabolic Nutrition

Metabolic Nutrition

Metabolic Nutrition – Scientifically Engineered Supplements for Peak Performance

At Cross the Limits, we are proud of our approach to stocking only the finest quality products for our customers, and Metabolic Nutrition supplements are no different. They’re a trusted brand with over 30 years of expertise in developing fitness supplements that truly work. Founded by a clinical pharmacist and nutritionist, Dr. Cohen, Metabolic Nutrition has revolutionised the supplement industry by focusing not just on the “coolness” factor, but mixing in precision, quality, and—most of all—scientifically validated formulations.