Cloma Pharma Methyldrene ECA 25 (Yellow)

The Cloma Pharma Methyldrene ECA consists of the following ingredients:

Slimming properties of Cao Mahuang

• strongly reduces appetite


• accelerates the metabolic rate, thus increasing energy expenditure


• intensifies thermogenesis or the process of heat energy production


• stimulates the release of fat from fat cells


• raises motivation for physical activity and adds energy

Anhydrous caffeine

Anhydrous caffeine is a purine alkaloid with a psychoactive effect. It naturally occurs in coffee, tea, guarana, yerba mate, and cocoa and is obtained synthetically. It belongs to stimulants or substances that stimulate the sympathetic and central nervous system (CNS).
Caffeine increases metabolism, the overall energy transformation occurring in the body, and promotes lipolysis, i.e., the breakdown of triglycerides in adipose tissue. In addition, blocking adenosine receptors counteracts sleepiness and reduces fatigue.

White willow bark

White willow bark – natural aspirin – contains salicin or natural acetylsalicylic acid. Then, caffeine and Cao Mahuang enter the “ECA stack” composition, a highly effective complex in burning off fat.

Salicylic acid

Salicylic acid can activate the AMP-dependent kinase enzyme (AMPK), which increases the supply of energy substrates to muscle cells and intensifies their combustion. In connection with this, the body’s energy expenditure increases, and fat loss becomes more important.

Bitter citrus extract (Citrus Aurantium Extract)

Bitter citrus extract (Citrus Aurantium Extract) contains Citrus aurantium (a natural analogue of Cao Mahuang), which stimulates the sympathetic nervous system like adrenaline. In addition, it activates some of the adrenergic receptors: alpha-1 and beta-3, which causes lipolysis (decomposition of fats) with simultaneous activation of thermogenesis.
Citrus aurantium is a natural substitute for Cao Mahuang. As a result, it is increasingly added to supplements and preparations intended for athletes and obese people.

Correct / Korean ginseng (Panax ginseng) (root extract)

Correct / Korean ginseng (Panax ginseng) (root extract) is a medicinal plant used in Chinese medicine for almost 4000 years. It contains numerous flavonoids, nitrogen compounds, fatty acids, vitamins, and bioactive ginsenosides classified as saponins. It belongs to the group of adaptogens, i.e. herbal substances (extracts) supporting the body’s resistance to stress stimuli and traumatic experiences, used in states of fatigue or anxiety. In addition, it helps to slim through a specific ability to lower blood glucose, improving insulin-glucose management.

Ginger root powder

Ginger root powder contains shogaole and gingerol – polyphenols with a similar structure to noradrenaline and facilitate fat burning. In addition, it favours slimming because it is included in compounds intensifying thermogenesis, which stimulates the body’s energy expenditure by increasing heat production.

Hoodia Gordonii

Hoodia Gordonii is a South African plant cultivar in the Hoodia family in the Kalahari Desert. Its active compound is steroid glycosides (hoodia in calogenin), whose activity is not fully known by science. However, as an effective suppressant of hunger, it is recommended for people who want to reduce body fat by increasing the rate of metabolism.

Cayenne fruit extract

Cayenne fruit extract extracted from hot chilli peppers; contains capsaicin (an alkaloid that acts on the vanilloid receptor). This releases adrenaline and norepinephrine (catecholamines) from the adrenal medulla, increasing metabolism and lipolysis.

Green tea extract (Green tea leaf extract)

Green tea extract (Green tea leaf extract) contains biologically active compounds, such as polyphenols (including catechin, EGCG – epigallocatechin gallate), showing antioxidant properties and low thermogenic potential.

Cocoa extract

Cocoa extract derived from cocoa beans contains theobromine, a purine alkaloid. When combined with polyphenols and caffeine, it increases the thermogenic potential, increasing energy expenditure and accelerating the reduction of body fat.

Black Griffonia seed extract

Black Griffonia seed extract contains 5-HTP (5-hydroxytryptophan) – an aromatic amino acid naturally produced by the body from an exogenous (essential) amino acid – L-tryptophan. It has been therapeutically used for over 30 years due to its ability to increase serotonin production in the brain.
Clinical studies on obese patients have shown that using 5-HTP decreased food intake (reduction of appetite) and, thus, reduced body weight.
This makes 5-HTP very helpful during restrictive weight-loss diets, when the amount of tryptophan and serotonin drops sharply. This results in increased carbohydrate desire and excessive caloric intake or gluttony. 5-HTP counteracts the craving for carbohydrates (about this sweetness) and thus helps to reduce the appetite and the number of calories consumed.