Helvetix Pharma BAM-15 60 Caps

Helvetix Pharma BAM-15 – Mitochondrial Uncoupler

BAM-15 (N5, N6-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine) is a modern, highly selective mitochondrial uncoupler. In the realm of advanced biochemistry and metabolic optimisation, this compound has gained significant attention as a refined alternative to classic uncoupling agents, offering superior precision at the cellular level.

Mechanism of Action: Protonophore Uncoupling

BAM-15 acts as a protonophore, facilitating the transport of protons across the inner mitochondrial membrane while bypassing ATP synthase. This process is known as uncoupling oxidative phosphorylation.

Unlike older generations of uncoupling agents, BAM-15 possesses unique characteristics:

• High Selectivity: It specifically targets mitochondrial membranes without depolarising the plasma membrane, maintaining overall cell viability.

• Metabolic Efficiency: It forces mitochondria to work harder, requiring them to consume more energy substrates to maintain the proton gradient.

• Broad Respiratory Window: It allows for a maximum rate of mitochondrial respiration over a wide range of concentrations without the cytotoxicity typically associated with other compounds.

Compound Data & Purity

The Helvetix Pharma formulation is engineered with the analytical rigour required for advanced experimental applications:

• Compound: BAM-15

• CAS Number: 210302-17-3

• Dosage: 25 mg per capsule

• Purity: $\ge 98\%$ verified via HPLC (High-Performance Liquid Chromatography)

• Quantity: 60 Capsules

• Excipients: Microcrystalline Cellulose, Magnesium Stearate, HPMC Capsule.

Why BAM-15?

In the scientific literature, BAM-15 is noted for its ability to increase energy expenditure without significantly affecting lean muscle mass or inducing excessive thermogenesis (body temperature spikes), unlike earlier compounds. It is a compound with high oral bioavailability, researched for its role in metabolic flexibility and cellular resilience.