Smart Brothers SLU-PP-332 is a modern metabolic support supplement designed to enhance energy production, improve endurance, and support the utilisation of fat. Each capsule delivers a potent 250 mcg of SLU-PP-332—a selective PPARδ agonist—used in the research community for its role in boosting metabolic rate, improving lipid oxidation, and supporting endurance performance at the cellular level.
Unlike traditional stimulants, SLU-PP-332 does not rely on central nervous system activation. Instead, it works by targeting the PPARδ pathway, a key regulator of genes responsible for maintaining energy homeostasis, enhancing mitochondrial efficiency, and regulating fatty acid metabolism. This makes it a powerful option for those seeking improved athletic performance, increased stamina, or fat-loss support without the crash or jittery side effects commonly associated with high-stimulant products.
Ingredient Breakdown:
SLU-PP-332 (250 mcg):
SLU-PP-332 is a synthetic PPARδ (Peroxisome Proliferator-Activated Receptor Delta) agonist, a class of compounds studied for their ability to increase energy metabolism and promote a shift in fuel usage from carbohydrates to fats. In preclinical trials, compounds of this class have demonstrated improvements in endurance, VO2 max, and exercise capacity while also increasing the expression of genes involved in mitochondrial biogenesis and fat oxidation.
PPARδ activation has also been associated with an increase in HDL (“good cholesterol”) and a reduction in triglycerides, adding value for those focused on body recomposition or metabolic health. While SLU-PP-332 remains a novel and experimental compound, its potential as a non-stimulant fat burner and endurance enhancer make it an exciting option for advanced users.
Who is it for?
Smart Brothers SLU-PP-332 is ideal for experienced athletes, advanced gym-goers, and biohackers looking to:
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Enhance metabolic rate without stimulants
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Improve endurance and performance
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Increase fat oxidation
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Support mitochondrial efficiency
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Promote leaner body composition over time
Due to the novel nature of this compound, it is recommended only for informed users who are familiar with PPAR agonists and metabolic regulators.
Dosage – Timing – Follow-Up
Dosage:
Take 1onecapsule daily with food. Do not exceed one capsule in 24 hours unless under professional guidance.
Timing:
Best taken in the morning or before physical activity to maximise metabolic and endurance benefits throughout the day.
Follow-Up:
Due to the research-level nature of SLU-PP-332, we recommend using it in 6–to 8–week cycles, followed by a 4-week break. Users should closely monitor their physical performance, sleep, and recovery during use.
Our Insights:
In our experience, the Smart Brothers SLU-PP-332 delivers noticeable improvements in stamina and energy after just 10 days. Unlike traditional fat burners, there are no jitters or crashes, and performance feels smoother and more sustained. This makes it particularly valuable for cardio sessions or when working on conditioning. The lack of central stimulation also means it pairs well with other thermogenics or nootropics without overstimulation.