SARMS – Selective androgen receptor modulators

The creators of SARMs aimed to create a supplement that stimulates the positive effects of androgens, i.e., male sex hormones, while eliminating their negative effects (including the risk of stroke, heart attack, atherosclerosis, kidney, skin, liver diseases, impotence, alopecia, mental disorders). They created a group of substances that resemble steroid hormones; they are very similar to steroids, as they bind to androgen receptors, changing DNA, which, thanks to this reaction, increases the ability of muscles to grow and improves one’s performance. They are not susceptible to enzymes that metabolize steroids (T and AAS). Thanks to SARMs, muscle tissue is built and fat reduction is induced; you can also notice faster regeneration of the body and improvement in bone density.

The advantage of SARMs over traditional steroids

• They have a weaker androgenic effect, which minimizes the occurrence of masculinizing changes in women – i.e., the appearance and intensity of male somatic features,

• They selectively activate and block receptors in the muscle and bone tissue; therefore, they can affect them in a positive way while eliminating negative effects at the same time,

• They are not susceptible to enzymes, so they do not form undesirable compounds (i.e., testosterone is not converted from 5-alpha-reductase to 5a-dihydrotestosterone),

• They do not have a negative effect on your brain, liver or prostate; they affect only specific tissues,

• They do not lead to aromatization of androgens into estrogens,

• They are used in medicine to alleviate muscle-wasting diseases (cancer, osteoporosis) and are also used as HRT – hormone replacement therapy agents.

Possible side effects

No studies have been conducted that could identify the adverse effects of long-term use of SARMs. If in the future this safer steroid substitute is carefully tested, it has the potential to be considered a safer version of testosterone therapy for the treatment of muscle deficiency, chronic fatigue syndrome, and osteoporosis.

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