Cloma Pharma Methyldrene ECA 25 (Yellow) 100 caps


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Cloma Pharma Methyldrene ECA is one of the most potent fat burners on the market of supplements for athletes. It contains only synergistically active ingredients, whose effectiveness has been confirmed by much scientific research. In addition, a potent dose of the proprietary “ECA” mix makes it one of the leaders of this type of product.

The Cloma Pharma Methyldrene ECA consists of the following ingredients:

Slimming properties of Bitter Orange Extract:

– strongly reduces appetite, reduces appetite

– accelerates the metabolic rate, thus energy expenditure

– intensifies thermogenesis or the process of heat energy production

– stimulates the release of fat on fat cells

– raises motivation for physical activity and adds energy

Anhydrous caffeine is a purine alkaloid with a psychoactive effect, naturally occurring among coffee, tea, guarana, yerba mate and cocoa, and obtained synthetically. It belongs to stimulants or substances that stimulate the sympathetic system and the central nervous system (CNS).

Caffeine increases the metabolism, the overall energy transformation occurring in the body, and promotes lipolysis, i.e. the breakdown of triglycerides with adipose tissue. In addition, blocking adenosine receptors counteracts sleepiness and reduces fatigue.

White willow bark – also called natural aspirin; contains salicin or natural acetylsalicylic acid. Then, caffeine and Bitter Orange Extract enter the “ECA stack” composition, a highly effective complex in burning back fat.

Salicylic acid can activate the AMP-dependent kinase enzyme (AMPK), which increases the supply of energy substrates to muscle cells and intensifies their combustion. In connection with this, the energy expenditure of the body increases, and fat loss is more important.

Bitter citrus extract (Citrus Aurantium Extract) – contains Citrus aurantium (a natural analogue of Bitter Orange Extract), which stimulates the sympathetic nervous system like adrenaline. In addition, it activates some of the adrenergic receptors: alpha-1 and beta-3, which causes lipolysis (decomposition of fats) with simultaneous activation of thermogenesis.

Citrus aurantium is a natural substitute for Bitter Orange Extract. As a result, it is more and more often added to supplements and preparations intended for athletes and obese people.

Correct / Korean ginseng (Panax ginseng) (root extract) – is a medicinal plant used in Chinese medicine for almost 4000 years. It contains numerous flavonoids, nitrogen compounds, fatty acids, vitamins, and bioactive ginsenosides classified as saponins. It belongs to the group of adaptogens, i.e. herbal substances (extracts) supporting the body’s resistance to stress stimuli and traumatic experiences, used in states of fatigue or anxiety. In addition, it helps to slim through a specific ability to lower blood glucose, improving insulin-glucose management.

Ginger root powder – contains shogaole and gingerol – polyphenols with a similar structure to noradrenaline and facilitate fat burning. In addition, it favours slimming because it is included in compounds intensifying thermogenesis, which stimulates the body’s energy expenditure by increasing heat production.

Hoodia Gordonii is a South African plant cultivar with the Hoodia family, occurring in the Kalahari desert. Its active compound is steroid glycosides (hoodie in calogenin), whose activity is not fully known by science. However, as an effective suppressant of hunger, it is recommended for people who want to reduce body fat by increasing the rate of metabolism.

Cayenne fruit extract – extracted from hot chilli peppers; contains capsaicin (an alkaloid that acts on the vanilloid receptor). This releases adrenaline and norepinephrine (catecholamines) from the adrenal medulla, resulting in increased metabolism and lipolysis.

Green tea extract – (Green tea leaf extract) – is a concentrate containing biologically active compounds: polyphenols (including catechin, EGCG – epigallocatechin gallate), showing antioxidant properties and low thermogenic potential.

Cocoa extract – derived from cocoa beans; contains theobromine – a purine alkaloid, combined with polyphenols and caffeine increases the thermogenic potential, increasing energy expenditure and accelerating the reduction of body fat.

Black Griffonia seed extract – contains 5-HTP (5-hydroxytryptophan) – an aromatic amino acid naturally produced by the body from an exogenous (essential) amino acid – l-tryptophan. She has been therapeutically used for over 30 years due to her ability to increase serotonin production in the brain.

Clinical studies on obese patients have shown that using 5-HTP decreased food intake (reduction of appetite) and, thus, decreased body weight.

All this makes 5-HTP very helpful during restrictive weight-loss diets, when both the amount of tryptophan and serotonin drops sharply, resulting in increased carbohydrate desire and consequently excessive caloric intake or gluttony. 5-HTP counteracts the craving for carbohydrates (about this sweetness) and thus helps to reduce the appetite and the number of calories consumed.

In conclusion, Cloma Pharma Methyldrene ECA is a highly effective fat burning that acts across various metabolic pathways. However, the preparation is intended only for advanced users and athletes due to the most potent ingredients on the market.


One capsule twice a day